
Accelerate your science with expert Sapio solutions
Karchem Consulting specializes in navigating the inherent complexities of modern laboratory informatics, helping scientists fully leverage the deep and often intricate feature set of the Sapio platform. Our team includes Sapio Platform Engineer certified consultants, and since our founding in 2018, we have become a trusted source for ELN/LIMS evaluation, implementation, and management for over 50 clients, ranging from established CLIA labs to early-stage startups.
As a Sapio Partner, we offer a comprehensive suite of services to help you master its extensive capabilities and optimize your scientific workflows, data management, and compliance. We understand that groundbreaking science requires sophisticated informatics solutions. Our consultants possess relevant scientific backgrounds, enabling us to deliver white-glove services tailored to each client’s unique needs and the specific configuration of their Sapio instance. Whether we are supplementing your existing lab informatics team or executing on a specific, intricate solution, you can count on Karchem Consulting to provide expert support and solutions.

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Implement data models from requirements gathering through validation across a variety of domains, including protein/antibody engineering, cell/gene therapy, and in vitro/in vivo.
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Plan and execute data migration.
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Configure Sapio Storage hierarchies and customize barcoded printer labels.
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Automate low inventory alerts and cleanup.
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Integrate instrument tracking and maintenance into workflows with automated notifications.
Process Optimization and Custom Solutions
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Design experiment templates and process queues with dynamic instructions, auto-calculations, and embedded logic.
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Automate tasks like sample plating, sample batching, and data backfill.
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Convert external Excel/sample accessioning data into structured records through Sapio’s Complex Data Loader (CDL) or custom webhooks.
Other Professional
Services
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Onboard and train users to client-specific needs.
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Evaluate and tailor Sapio permissions and user groups.
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Design home page, toolbar, and reports to tailor user interface (UI).
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Coach best practices for e-signatures, change management, SDLC, and Agentic AI (ELaiN).
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Analyze Sapio's fit within data architecture and identify integration points.
Lab Automation and Instrument Integration
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Build end-to-end workflows between Sapio and automated liquid handlers (Hamilton, TECAN).
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Integrate instruments using Sapio Jarvis and other Scientific Data Cloud (SDMS) solutions.
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Transform raw instrument output (CSV, XML) into normalized data via ETL logic.
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Automate event-driven data pipelines using custom webhooks and rules.
Sapio-Powered Molecular Informatics
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Set up chemical and biological material tracking with Plasmid Editor, Molecule Designer, and Chemistry Tools.
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Curate sequencing index sets with multiplex batches.
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Engineer workflows for codon optimization, plasmid assembly, sequencing pipelines, and compound registration with built-in QC logic.
Computer Software Assurance (CSA) and Computer Software Validation (CSV)
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Manage and advise on end-to-end system validation in accordance with FDA and GAMP best practices.
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Develop comprehensive validation documentation, including Validation Plan, User Requirements Specification (URS), Functional and Design Specifications, Requirements Traceability Matrix, System Standard Operating Procedures (SOPs), and Validation Summary Report.
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Create and execute robust test scripts.
